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Animated Cycloadduct


The cycloadduct (12) can be shown as an animated 3D model. The top methyl group of the silyl enol ether side chain at position C-9 has been cropped.
[legend: Carbon atom = grey, hydrogen = light blue, Oxygen = red and Silicon = purple]

two seconds between frames; 21 frames
Compare this with the D-glucose based diene (4):



Or as the preferred conformer [which is reversibly formed from (4) via a trans-butadiene intermediate], whereby a dienophile will bond itself to the top face of the diene:


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